Ordinary Adjustment | Solactive US Biohealthcare Index | Effective Date 1st October 2025
Solactive US Biohealthcare Index:
In the ordinary adjustment, the following composition will be implemented effective open 1st October 2025:
| ACADIA PHARMACEUTICALS INC |
| ADAPTIVE BIOTECHNOLOGIES CORP |
| ADMA BIOLOGICS INC |
| AGIOS PHARMACEUTICALS INC |
| AKERO THERAPEUTICS INC |
| ALKERMES PLC |
| ALNYLAM PHARMACEUTICALS INC |
| AMGEN INC |
| AMICUS THERAPEUTICS INC |
| ANI PHARMACEUTICALS INC |
| APOGEE THERAPEUTICS ORD |
| ARCELLX INC |
| ARCUTIS BIOTHERAPEUTICS INC |
| ARGENX SE – ADR |
| ARROWHEAD PHARMACEUTICALS INC |
| ASCENDIS PHARMA A/S |
| ATRICURE INC |
| AVIDITY BIOSCIENCES INC |
| AXSOME THERAPEUTICS INC |
| BEAM THERAPEUTICS INC |
| BEONE MEDICINES LTD-ADR |
| BIOCRYST PHARMACEUTICALS INC |
| BIOGEN INC |
| BIOMARIN PHARMACEUTICAL INC |
| BIONTECH SE |
| BRIDGEBIO PHARMA INC |
| CARIS LIFE SCIENCES INC |
| CATALYST PHARMACEUTICALS INC |
| CENTESSA PHARMACEUTICALS-ADR |
| CG ONCOLOGY INC |
| CIDARA THERAPEUTICS INC |
| COGENT BIOSCIENCES INC |
| CORCEPT THERAPEUTICS INC |
| CRINETICS PHARMACEUTICALS INC |
| CRISPR THERAPEUTICS AG |
| DENALI THERAPEUTICS INC |
| DISC MEDICINE INC |
| DYNAVAX TECHNOLOGIES CORP |
| DYNE THERAPEUTICS INC |
| EDGEWISE THERAPEUTICS INC |
| ENLIVEN THERAPEUTICS INC |
| EXACT SCIENCES CORP |
| EXELIXIS INC |
| GENMAB A/S |
| GILEAD SCIENCES INC |
| GRAIL INC |
| GUARDANT HEALTH INC |
| HALOZYME THERAPEUTICS INC |
| HARMONY BIOSCIENCES HOLDINGS INC |
| HOLOGIC INC |
| IDEAYA BIOSCIENCES INC |
| IMMUNITYBIO INC |
| IMMUNOCORE HOLDINGS PLC |
| INCYTE CORP |
| INNOVIVA INC |
| IRHYTHM TECHNOLOGIES INC |
| JANUX THERAPEUTICS INC |
| JAZZ PHARMACEUTICALS PLC |
| KRYSTAL BIOTECH INC |
| KYMERA THERAPEUTICS INC |
| LEGEND BIOTECH CORP |
| LIVANOVA PLC |
| MADRIGAL PHARMACEUTICALS INC |
| MERIT MEDICAL SYSTEMS INC |
| MERUS BV |
| METSERA INC |
| MIRUM PHARMACEUTICALS INC |
| MODERNA INC |
| NATERA INC |
| NEUROCRINE BIOSCIENCES INC |
| NEWAMSTERDAM PHARMA CO NV |
| Nuvalent Inc |
| PROTAGONIST THERAPEUTICS INC |
| PTC THERAPEUTICS INC |
| REVOLUTION MEDICINES INC |
| RHYTHM PHARMACEUTICALS INC |
| SAREPTA THERAPEUTICS INC |
| SCHOLAR ROCK HOLDING CORP |
| SOLENO THERAPEUTICS INC |
| SUMMIT THERAPEUTICS PLC |
| SUPERNUS PHARMACEUTICALS INC |
| TARSUS PHARMACEUTICALS INC |
| TEMPUS AI INC |
| ULTRAGENYX PHARMACEUTICAL INC |
| VERACYTE INC |
| VERONA PHARMA PLC – ADR |
| VERTEX PHARMACEUTICALS INC |
| XENON PHARMACEUTICALS INC |
| ZAI LAB LTD |