Ordinary Adjustment | Solactive Pharma & Biotech Opportunity Index | February 2019

In the ordinary index rebalance, the following changes will be implemented:

YUHAN CORP ORD
CHINA TRADITIONAL CHINESE MEDICINE HOLDINGS CO LTD
CHINA MEDICAL SYSTEM HOLDINGS LTD
SINOPHARM GROUP CO LTD
SINO BIOPHARMACEUTICAL LTD ORD
3SBIO INC
LUYE PHARMA GROUP LTD
SHIONOGI & CO LTD ORD
NIPPON SHINYAKU CO LTD
ONO PHARMACEUTICAL CO LTD ORD
SANTEN PHARMACEUTICAL CO LTD ORD
SAWAI PHARMACEUTICAL CO LTD ORD
APHRIA INC
BLUEBIRD BIO INC
BTG PLC
CARDINAL HEALTH INC
CHINA BIOLOGIC PRODUCTS HOLD
CATALENT INC
GRIFOLS SA CLASS A
HIKMA PHARMACEUTICALS PLC
HYPERA SA
JAZZ PHARMACEUTICALS PLC
LIGAND PHARMACEUTICALS INC
MEDPACE HOLDINGS INC
MERCK KGAA
MYLAN NV
SYNEOS HEALTH INC
UCB SA
UNITED THERAPEUTICS CORP
XENCOR INC