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Ordinary Adjustment | European Biotech Index (Total Return) (EUR) | Effective Date 8th October 2025

European Biotech Index (Total Return) (EUR):

In the ordinary adjustment, the following composition will be implemented over a period starting on 1st October 2025 cob and ending on 7th October 2025 cob. The new composition will be fully reflected in the index with effective open 8th October 2025:

ADVANCED MEDICAL SOLUTIONS GROUP PLC
ALK-ABELLO A/S
AMBU AS CLASS B
AVACTA GROUP PLC
BAVARIAN NORDIC A/S
BIONTECH SE
CHEMOMETEC A/S
DBV TECHNOLOGIES SA
DERMAPHARM HOLDING SE
DRAEGERWERK VZ
EL.EN. S.P.A.
EVOTEC SE
FAES FARMA SA
GENUS PLC
GERRESHEIMER AG
GRIFOLS SA CLASS A
HIKMA PHARMACEUTICALS PLC
LABORATORIOS FARMACEUTICOS R
ORION OYJ CLASS B
ORYZON GENOMICS
OXFORD INSTRUMENTS PLC
OXFORD NANOPORE TECHNOLOGIES PLC
PHARMA MAR SA
PHARMING GROUP NV
SARTORIUS AG PREF
SWEDISH ORPHAN BIOVITRUM AB
VALNEVA SE
VITROLIFE AB