Acquisition | BLUEPRINT MEDICINES CORP | 17th July 2025

On June 2, 2025, BLUEPRINT MEDICINES CORP and SANOFI SA entered into an agreement under which SANOFI will acquire BLUEPRINT. Under the terms of the agreement, SANOFI is offering BLUEPRINT shareholders USD 129 plus one contingent value right per each share held. The tender offer is scheduled to expire one minute following 11:59 P.M., Eastern Time, on July 16, 2025, unless the offer is otherwise extended or earlier terminated. The subsequent merger is tentatively scheduled to close prior to the market open on July 17, 2025. Trading in shares of BLUEPRINT MEDICINES CORP is expected to be halted effective July 17, 2025. Due to the presence of a contingent value right in the offer, BLUEPRINT MEDICINES CORP will be removed at its last close price effective (open) July 17, 2025.

The treatment below will be applied to the following indices:

• BLUEPRINT MEDICINES CORP will be removed from the Index.
• The weight of BLUEPRINT MEDICINES CORP (BPMC.OQ) based on its last close price will be distributed pro rata to remaining Index constituents.
• Effective Date (open): 17/07/2025

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