Spin Off | ALKERMES PLC | 16th November 2023

On November 2, 2022, ALKERMES PLC announced a spin-off of its oncology business, MURAL ONCOLOGY PLC. The distribution ratio will be One MURAL ONCOLOGY PLC Ordinary Share for every ten ALKERMES PLC held. The when-issued market of ALKERMES PLC and the when-issued market for MURAL ONCOLOGY PLC Ordinary Shares will begin trading on Nasdaq on Friday, November 3, 2023. The effective date for the spin off being November 16, 2023.

The treatment below will be applied to the following indices:

• The spin-off company MURAL ONCOLOGY PLC will be added to the Index according to the transaction terms.
• Effective Date (open): 16/11/2023

Franklin US Core Index PR
Franklin US Core Index NTR
Franklin US Core Index TR
Knights of Columbus U.S. All Cap Index
Knights of Columbus U.S. All Cap Index PR
Enhanced Consciousness Index
RAFI Dynamic Multi-Factor Developed ex-U.S. Index NTR
RAFI Dynamic Multi-Factor Developed ex-U.S. Index PR
RAFI Dynamic Multi-Factor Developed ex-U.S. Index TR
RAFI Dynamic Multi-Factor Developed ex US Americas NTR Index
RAFI Dynamic Multi-Factor Developed ex US Americas PR Index
RAFI Dynamic Multi-Factor Developed ex US Americas GTR Index
RAFI Fundamental Global All Company Index NTR
RAFI Fundamental Global All Company Index PR
RAFI Fundamental Global All Company Index GTR
RAFI Multi-Factor Developed EUR Index NTR
RAFI Multi-Factor Developed Index NTR (GBP)
RAFI Multi-Factor Developed EUR Index PR
RAFI Multi-Factor Developed ex Low Volatility NTR
RAFI Multi-Factor Developed ex Low Volatility PR
RAFI Multi-Factor Developed ex Low Volatility GTR
RAFI Multi-Factor Developed Index NTR
RAFI Multi-Factor Developed Index PR
RAFI Multi-Factor Developed Index TR
Solactive GBS Developed Markets All Cap USD Index NTR
Solactive GBS Developed Markets All Cap USD Index PR
Solactive GBS Developed Markets All Cap USD Index TR
Solactive Developed Markets Healthcare Mid & Small Cap Index NTR
Solactive Developed Markets Healthcare Mid & Small Cap Index PR
Solactive Developed Markets Healthcare Mid & Small Cap Index TR
Solactive GBS Developed Markets Investable Universe EUR Index NTR
Solactive GBS Developed Markets Investable Universe EUR Index PR
Solactive GBS Developed Markets Investable Universe EUR Index TR
Solactive GBS Developed Markets Investable Universe USD Index NTR
Solactive GBS Developed Markets Investable Universe USD Index PR
Solactive GBS Developed Markets Investable Universe USD Index TR
Solactive GBS Developed Markets Small Cap USD Index NTR
Solactive GBS Developed Markets Small Cap USD Index PR
Solactive GBS Developed Markets Small Cap USD Index TR
Solactive ISS ESG Screened Developed Markets Small Cap Index NTR
Solactive ISS ESG Screened Developed Markets Small Cap Index PR
Solactive ISS ESG Screened Developed Markets Small Cap Index TR
Solactive ISS ESG Screened USA Small Cap Index NTR
Solactive ISS ESG Screened USA Small Cap Index PR
Solactive ISS ESG Screened USA Small Cap Index TR
Solactive GBS Global Markets Americas All Cap USD Index NTR
Solactive GBS Global Markets Americas All Cap USD Index PR
Solactive GBS Global Markets Americas All Cap USD Index TR
Solactive GBS Global Markets Americas Small Cap USD Index NTR
Solactive GBS Global Markets Americas Small Cap USD Index PR
Solactive GBS Global Markets Americas Small Cap USD Index TR
Solactive GBS Global Markets All Cap EUR Index NTR
Solactive GBS Global Markets All Cap EUR Index PR
Solactive GBS Global Markets All Cap EUR Index TR
Solactive GBS Global Markets All Cap USD Index NTR
Solactive GBS Global Markets All Cap USD Index PR
Solactive GBS Global Markets All Cap USD Index TR
Solactive GBS Global Markets Investable Universe EUR Index NTR
Solactive GBS Global Markets Investable Universe EUR Index PR
Solactive GBS Global Markets Investable Universe EUR Index TR
Solactive GBS Global Markets Investable Universe CHF Index NTR
Solactive GBS Global Markets Investable Universe CHF Index PR
Solactive GBS Global Markets Investable Universe CHF Index TR
Solactive GBS Global Markets Investable Universe USD Index NTR
Solactive GBS Global Markets Investable Universe USD Index PR
Solactive GBS Global Markets Investable Universe USD Index TR
Solactive GBS Global Markets Mid & Small Cap USD Index NTR
Solactive GBS Global Markets Mid & Small Cap USD Index PR
Solactive GBS Global Markets Mid & Small Cap USD Index TR
Solactive GBS Global Markets Small Cap USD Index NTR
Solactive GBS Global Markets Small Cap USD Index PR
Solactive GBS Global Markets Small Cap USD Index TR
Solactive GFS United States 800 Growth Style MV Index NTR
Solactive GFS United States 800 Growth Style MV Index PR
Solactive GFS United States 800 Growth Style MV Index TR
Solactive GFS United States 2500 Growth Style MV Index NTR
Solactive GFS United States 2500 Growth Style MV Index PR
Solactive GFS United States 2500 Growth Style MV Index TR
Solactive GFS United States 1000 Growth Style Index NTR
Solactive GFS United States 1000 Growth Style Index PR
Solactive GFS United States 1000 Growth Style Index TR
Solactive GFS United States 600 Growth Style Index NTR
Solactive GFS United States 600 Growth Style Index PR
Solactive GFS United States 600 Growth Style Index TR
Solactive GFS United States 1500 Growth Style Index NTR
Solactive GFS United States 1500 Growth Style Index PR
Solactive GFS United States 1500 Growth Style Index TR
Solactive GFS United States 400 + 600 Growth Style Index NTR
Solactive GFS United States 400 + 600 Growth Style Index PR
Solactive GFS United States 400 + 600 Growth Style Index TR
Solactive GBS North America All Cap USD Index NTR
Solactive GBS North America All Cap USD Index PR
Solactive GBS North America All Cap USD Index TR
Solactive GBS North America Investable Universe CHF Index NTR
Solactive GBS North America Investable Universe CHF Index PR
Solactive GBS North America Investable Universe CHF Index TR
Solactive GBS North America Small Cap USD Index NTR
Solactive GBS North America Small Cap USD Index PR
Solactive GBS North America Small Cap USD Index TR
Solactive Evaluate Global Pharma Index NTR
Solactive Evaluate Global Pharma Index PR
Solactive Evaluate Global Pharma Index TR
Solactive Gerd Kommer Multifactor Equity Index NTR
Solactive Gerd Kommer Multifactor Equity Index PR
Solactive Gerd Kommer Multifactor Equity Index TR
Solactive SoFi US Next 500 Growth Index
Solactive SoFi US Next 500 Growth Index (NTR) (INTERNAL)
Solactive SoFi US Next 500 Growth Index (PR) (INTERNAL)
Solactive US Broad Market Index (GTR)
Solactive US Broad Market Index (PR)
Solactive United States Biotechnology Index NTR
Solactive United States Biotechnology Index PR
Solactive United States Biotechnology Index TR
Solactive US Extended Broad Market Index (GTR)
Solactive US Large & Mid Cap Index (GTR)
Solactive US Large & Mid Cap Index (PR)
Solactive US Small & Mid Cap Index (GTR)
Solactive US Small & Mid Cap Index (PR)
Solactive ISS ESG Screened Paris Aligned Developed Markets Small Cap Index NTR
Solactive ISS ESG Screened Paris Aligned Developed Markets Small Cap Index PR
Solactive ISS ESG Screened Paris Aligned Developed Markets Small Cap Index TR
Solactive Smart Health Care PR Index
Solactive Smart Health Care GTR Index
Solactive United States 800 Index NTR
Solactive United States 800 Index
Solactive United States 800 Index TR
Solactive United States 2500 Index NTR
Solactive United States 2500 Index
Solactive United States 2500 Index TR
Solactive United States 1000 Index NTR
Solactive United States 1000 Index
Solactive United States 1000 Index TR
Solactive United States 3000 Index NTR
Solactive United States 3000 Index
Solactive United States 3000 Index TR
Solactive GBS United States All Cap Index NTR
Solactive GBS United States All Cap Index PR
Solactive GBS United States All Cap Index TR
Solactive GBS United States Investable Universe Index NTR
Solactive GBS United States Investable Universe Index PR
Solactive GBS United States Investable Universe Index TR
Solactive GBS United States Large & Mid Cap Equal Weight Index NTR
Solactive GBS United States Large & Mid Cap Equal Weight Index PR
Solactive GBS United States Large & Mid Cap Equal Weight Index TR
Solactive GBS United States Mid & Small Cap Index NTR
Solactive GBS United States Mid & Small Cap Index PR
Solactive GBS United States Mid & Small Cap Index TR
Solactive GBS United States Small Cap Index NTR
Solactive GBS United States Small Cap Index PR
Solactive GBS United States Small Cap Index TR
Solactive GFS United States 800 Value Style MV Index NTR
Solactive GFS United States 800 Value Style MV Index PR
Solactive GFS United States 800 Value Style MV Index TR
Solactive GFS United States 1000 Value Style MV Index NTR
Solactive GFS United States 1000 Value Style MV Index PR
Solactive GFS United States 1000 Value Style MV Index TR
Solactive GFS United States 2500 Value Style MV Index NTR
Solactive GFS United States 2500 Value Style MV Index PR
Solactive GFS United States 2500 Value Style MV Index TR
Solactive GFS United States 3000 Value Style MV Index NTR
Solactive GFS United States 3000 Value Style MV Index PR
Solactive GFS United States 3000 Value Style MV Index TR
Solactive GFS United States 1000 Value Style Index NTR
Solactive GFS United States 1000 Value Style Index PR
Solactive GFS United States 1000 Value Style Index TR
Solactive GFS United States 600 Value Style Index NTR
Solactive GFS United States 600 Value Style Index PR
Solactive GFS United States 600 Value Style Index TR
Solactive GFS United States 1500 Value Style Index NTR
Solactive GFS United States 1500 Value Style Index PR
Solactive GFS United States 1500 Value Style Index TR
Solactive GFS United States 400 + 600 Value Style Index NTR
Solactive GFS United States 400 + 600 Value Style Index PR
Solactive GFS United States 400 + 600 Value Style Index TR
Solactive GBS Developed Markets ex Japan All Cap USD Index NTR
Solactive GBS Developed Markets ex Japan All Cap USD Index PR
Solactive GBS Developed Markets ex Japan All Cap USD Index TR
Solactive GBS Developed Markets ex Japan Small Cap USD Index NTR
Solactive GBS Developed Markets ex Japan Small Cap USD Index PR
Solactive GBS Developed Markets ex Japan Small Cap USD Index TR
Solactive GBS Developed Markets ex Switzerland Investable Universe CHF Index NTR
Solactive GBS Developed Markets ex Switzerland Investable Universe CHF Index PR
Solactive GBS Developed Markets ex Switzerland Investable Universe CHF Index TR
Solactive GBS United States 1500 Index
Solactive GBS United States 1500 Index NTR
Solactive GBS United States 1500 Index TR
Solactive GBS United States 600 Index
Solactive GBS United States 600 Index NTR
Solactive GBS United States 600 Index TR
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