Ordinary Reweighting | Solactive Europe & US Top Pharmaceuticals 2020 AR 3.5% Index | Effective Date 3rd January 2023

In the ordinary reweighting, the following index composition will be implemented effective open 03.01.2023:

ABBVIE INC
ASTRAZENECA PLC
BRISTOL-MYERS SQUIBB CO
JOHNSON & JOHNSON
MERCK & CO. INC.
NOVARTIS AG
NOVO NORDISK A/S
PFIZER INC
ROCHE HOLDING AG
SANOFI SA