Ordinary Adjustment | SOLACTIVE PHARMA & BIOTECH OPPORTUNITY INDEX | November 2018

In the ordinary rebalance the following composition will be implemented:

YUHAN CORP ORD
CHINA TRADITIONAL CHINESE MEDICINE HOLDINGS CO LTD
CHINA MEDICAL SYSTEM HOLDINGS LTD
SINOPHARM GROUP CO LTD
SINO BIOPHARMACEUTICAL LTD ORD
3SBIO INC
LUYE PHARMA GROUP LTD
ONO PHARMACEUTICAL CO LTD ORD
SANTEN PHARMACEUTICAL CO LTD ORD
SAWAI PHARMACEUTICAL CO LTD ORD
ALKERMES PLC
ALNYLAM PHARMACEUTICALS INC
APHRIA INC
BLUEBIRD BIO INC
BTG PLC
CHINA BIOLOGIC PRODUCTS HOLD
CHARLES RIVER LABORATORIES
DECHRA PHARMACEUTICALS PLC
HORIZON PHARMA PLC
IONIS PHARMACEUTICALS INC
JAZZ PHARMACEUTICALS PLC
MALLINCKRODT PHARMACEUTICALS
MYLAN NV
NEKTAR THERAPEUTICS
OPKO HEALTH INC
REPLIGEN CORP
REGENXBIO INC
SYNEOS HEALTH INC
UCB SA
XENCOR INC